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Esther K Schmitt Selected Research

NITD 609

1/2022High Prevalence of Plasmodium falciparum K13 Mutations in Rwanda Is Associated With Slow Parasite Clearance After Treatment With Artemether-Lumefantrine.
1/2022Efficacy of Cipargamin (KAE609) in a Randomized, Phase II Dose-Escalation Study in Adults in Sub-Saharan Africa With Uncomplicated Plasmodium falciparum Malaria.
12/2021Hepatic safety and tolerability of cipargamin (KAE609), in adult patients with Plasmodium falciparum malaria: a randomized, phase II, controlled, dose-escalation trial in sub-Saharan Africa.
7/2020The early preclinical and clinical development of cipargamin (KAE609), a novel antimalarial compound.
9/2010Spiroindolones, a potent compound class for the treatment of malaria.

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Esther K Schmitt Research Topics

Disease

7Malaria
01/2022 - 07/2010
4Infections
12/2021 - 06/2012
2Falciparum Malaria (Plasmodium falciparum Malaria)
01/2022 - 12/2021
1Fascioliasis
12/2019
1Inflammation (Inflammations)
07/2017
1Neoplasms (Cancer)
08/2015

Drug/Important Bio-Agent (IBA)

5NITD 609IBA
01/2022 - 09/2010
4Pharmaceutical PreparationsIBA
07/2020 - 06/2012
2Lumefantrine Drug Combination Artemether (Coartem)FDA Link
01/2022 - 12/2021
2Antimalarials (Antimalarial Agents)IBA
07/2020 - 06/2012
1artemisinin (artemisinine)IBA
01/2022
1TriclabendazoleIBA
12/2019
1indoleacrylic acidIBA
07/2017
1Peptide Elongation Factor 1 (EF-1)IBA
08/2015
1Carbolines (Beta-Carbolines)IBA
07/2010

Therapy/Procedure

1Therapeutics
01/2022